The grounding number: GeneBench Pro 37.8% — the weakest domain score Astra publishes
GeneBench Pro is GPT-6: Astra's weakest published domain score at 37.8%, well behind its scores in coding, cybersecurity, and general reasoning. State this plainly rather than burying it: genomics and life-sciences reasoning is not where this model is strongest, and it should not anchor a life-sciences workflow decision on its headline frontier scores elsewhere.
Example prompt
Organize the attached set of paper abstracts by method and finding, flag contradictory results between papers, and list the specific claims a domain scientist should verify before citing any of them.Who should look elsewhere
If genomics-specific reasoning accuracy is the primary requirement, look for a domain-specialized model or tool benchmarked directly on genomics tasks rather than a general frontier model whose GeneBench Pro score sits well below its other domain scores.
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